Lily Poisoning in Cats: Every Part Is Deadly — Emergency Guide
Published: 2026-06-02 · Updated: 2026-06-02
Which Lilies Are Toxic?The following genera cause acute renal failure in cats: Lilium (Easter lily, Tiger lily, Stargazer lily, Asiatic lily, Oriental lily) and Hemerocallis (Daylily). NOT toxic: Peace lily (Spathiphyllum), Calla lily (Zantedeschia), and Peruvian lily...
⚠ Toxicity Profile
| Danger Level | Extreme (Emergency) |
|---|---|
| Toxic Dose Limit | Varies mg/kg |
| Target Organ | Multiple Organs |
Which Lilies Are Toxic?
The following genera cause acute renal failure in cats: Lilium (Easter lily, Tiger lily, Stargazer lily, Asiatic lily, Oriental lily) and Hemerocallis (Daylily). NOT toxic: Peace lily (Spathiphyllum), Calla lily (Zantedeschia), and Peruvian lily (Alstroemeria) — these contain insoluble calcium oxalate crystals that cause oral irritation but not renal failure. The toxic principle in true lilies has not been conclusively identified — the nephrotoxin appears to be a water-soluble compound present in all plant parts.
Clinical Progression
- 0-2 hours: Vomiting, hypersalivation, depression, anorexia
- 12-24 hours: Polyuria (excessive urination) as renal tubules lose concentrating ability, followed by oliguria (decreased urine output)
- 24-48 hours: BUN and creatinine begin to rise, isosthenuria (urine specific gravity 1.008-1.012), renal tubular epithelial casts on urinalysis
- 48-72 hours: Anuric renal failure (no urine production), severe azotemia, hyperkalemia, death without hemodialysis
Emergency Treatment Protocol
Recent ingestion (<6 hours): induce emesis, administer activated charcoal. All cases: aggressive IV fluid diuresis (2-3× maintenance rate) for 48 hours minimum to maintain renal perfusion and flush nephrotoxin. Monitor urine output every 4 hours. If oliguria or anuria develops despite fluids, hemodialysis or peritoneal dialysis is the only treatment option — available at university veterinary teaching hospitals. Prognosis: >90% survival with treatment within 18 hours; <50% survival if treatment begins after 18 hours; near 0% survival once anuric renal failure is established.
🔬 Pet Toxicity Risk Evaluator
Enter your pet's weight and the estimated amount consumed to assess toxicity risk — calculated locally in your browser.
🚨 If Your Pet Has Been Exposed
DO NOT WAIT for symptoms to appear. Contact your veterinarian or the ASPCA Animal Poison Control Center at (888) 426-4435 immediately. Have your pet's weight, the substance involved, estimated amount consumed, and time of ingestion ready. The risk calculator above is an educational estimate only — individual animal responses vary based on age, breed, pre-existing conditions, and concurrent substance ingestion.
References & Further Reading
- ASPCA Animal Poison Control Center. Animal Poison Control FAQ. aspca.org/pet-care/animal-poison-control
- U.S. Food & Drug Administration, Center for Veterinary Medicine. Animal Health & Safety. fda.gov/animal-veterinary
- National Institutes of Health, PubMed. Veterinary Toxicology Research Database. pubmed.ncbi.nlm.nih.gov
- Pet Poison Helpline. 24/7 Animal Poison Control Emergency Service. petpoisonhelpline.com
Citations are provided for educational reference. Content is reviewed periodically but does not replace professional veterinary advice. If your pet shows signs of illness, contact a licensed veterinarian immediately.